High acid diet increases the risk of end-stage renal disease

Author: Leo
Keywords: DAL | ESRD | High acid | Advanced nephropathy | eGFR

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Guidance
A study published in the latest issue of JASN suggests that if a patient with chronic kidney disease has a high acid content diet, it may increase the risk of kidney failure. Previously, small clinical trials showed that reducing dietary acid load (DAL) could improve renal injury and delay renal dysfunction.
A study published in the latest issue of JASN suggests that if a patient with chronic kidney disease has a high acid content diet, it may increase the risk of kidney failure. Patients with chronic kidney disease may want to limit the intake of meat and increase the fruits and vegetables to help protect their kidneys.
Previously, small clinical trials showed that reducing dietary acid load (DAL) could improve renal injury and delay renal dysfunction. However, the relationship between DAL and the risk of developing end-stage renal disease (ERSD) in patients with chronic kidney disease (CKD) is unclear. Dr. Tanushree of the University of California, San Francisco, and her colleagues, in order to study the problem, collected 1486 representative samples of CKD adults in the United States, tested DAL by quantifying the net acid excretion (NAEes), and tracked patients with nephropathy development of. After a 2 - year follow - up, follow the ERSD health care registration to confirm whether there is advanced kidney disease.
Researchers used FINE-GRAY to assess the association between DAL and ERSD (taking into account demographic, nutritional, clinical, renal / injury markers, etc.). The results showed that 311 (20.9%) participants developed ERSD, high DAL levels increased ESRD associated risk - relative risk (95% confidence interval) was 3.04 (1.58 ~ 5.86) was high, 1.81 (0.89 ~ 3.68) Level. Participants with proteinuria, high DAL showed a strong association with the risk of ESRD. So a higher level of dietary acid load is strongly associated with the development of renal failure. Consumers who consume high-acid diets may develop three times higher than those who consume low-acid diets in developing renal failure.

The low-acid diet diet includes a wide range of fruits and vegetables, while the high acid diet contains more meat. Suffering from chronic kidney disease may be more attention to diet in the acid-rich foods to reduce the development of renal failure may be, while listening to the doctor suggested that taking drugs to avoid nephrotoxin. Dr. Tanushree said: dialysis treatment to bring high cost and poor quality of life can be used to avoid a more healthy diet rich in fruits and vegetables.

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