Author: Leo
Keywords: organ | pluripotent stem cells | cell type | growth
differentiation
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Successful use of stem cells in the laboratory to cultivate a human root tissue with a preliminary growth state, and this process leads to the development of full-featured transplanting organs in the laboratory and a step further.
The same time as the above-
In a study published in the international journal Nature, scientists from Australia and the Netherlands have shown that they have successfully used stem cells to develop human kidney tissue with initial growth in the laboratory, and this process leads to In the laboratory to develop full-featured transplant organs and a step further.
Researchers say that this organization is not a dynamic organization, but can be used for other purposes, such as drug toxicity test used to replace the animal model. Researchers in the article using induced pluripotent stem cells (iPS) to create a kidney-like structure. At present, the use of stem cells to produce human organs has long been a major research barrier in the scientific community because of the serious lack of donated organs to transplant patients or patients with disease-damaged patients.
Scientists need to induce stem cells to differentiate themselves into kidneys, liver and lung cells, and then these cells form a true organ with complex anatomical structures and then play a role in recipient patients. In this latest study, the researchers managed to transform pluripotent stem cells into two different types of adult cells. Researchers Davies said that the culture product is not a kidney, but only a kind of organ, of course, as a useful clinical use of transplant organs also need a long way.
Researchers point out that this type of organ may help to complete a different medical need, that is, to detect the safety of new drugs in human bodies, and that the type of cells that are susceptible to drug damage has been found in organs; stem cells are The original cells, with its growth and differentiation to form a variety of special types of cells, it will form a different organ, such as the brain, heart, kidney and so on.
Until a few years ago, when the induction of pluripotent stem cells was developed to create, the only way to obtain stem cells was obtained from human embryos, and the current destruction of human embryos to obtain stem cells in the scientific community was controversial. At present, other research teams have also reported in the laboratory using pluripotent stem cells to cultivate the "organ" stomach, liver, retina, brain and heart tissue.
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