Author: Leo
Keywords: kidney disease
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| From google images |
Li told reporters tonight.
Originally, the 53-year-old mother Li, recently from the countryside to visit the little grandson, due to fatigue on the way, unfortunately infected with pneumonia. She is coughing, sputum, and fever, is now living in the hospital. After the doctor's active treatment, the burning has begun to retreat. A few days down, weighing only 50 kg. Yesterday blood test, but also found that elevated urea nitrogen, listening to people say that elevated blood urea is a poor performance of renal function. This can be tired of the teacher Li. He said anxiously: "Mother at home, but a healthy person, all the way from the countryside to see grandchildren, all the way dust, infected with pneumonia is not good, which found that renal function is not good in the future how do I explain to the brothers "He asked me with a puzzled look:" Professor, you are a kidney specialist, you said my mother normal renal function? Or need to do what check?
Took Li teacher handed the test alone, I saw the above read blood urea nitrogen 10.2mmol / L (normal 2.9 ~ 7.5), serum creatinine 50μmol / L (normal 53 ~ 115). I told Li, to answer his question, first of all to understand what the function of the kidney? What are the commonly used renal function tests? Why should blood creatinine, urea nitrogen?
The main function of the kidney is to generate urine. Urine production first through the glomerular filtration, and then by the renal tubular reabsorption and secretion, resulting in concentrated urine. Therefore, the kidneys through the urinary effect, to exclude the body's metabolic waste and excess biochemical substances and drugs and other harmful substances, to retain the body of useful substances, adjust the body fluid capacity. In other words, the kidney has the function of "going to its left and leaving it". Once this function is impaired, the body's metabolic waste will accumulate, and the body of toxic effects, the internal environment out of balance, and then a series of renal dysfunction.
The main indicators of glomerular function are serum creatinine and urea nitrogen. Blood creatinine is released by the process of muscle metabolism. Currently recognized by the medical profession, serum creatinine if combined with the patient's age and weight considerations is the best indicator of glomerular function. Clinical practice and commonly used the following formula, the creatinine clearance rate was calculated from serum creatinine. Creatinine clearance (ml / min) = [(140- years old) × kg body weight] ÷ [72 × creatinine (mg)] If female, the value of the above formula, then multiply 0.85.
The creatinine clearance rate varies with gender, age, and weight. Adult male creatinine clearance rate of about 120 ml / min, age, creatinine clearance rate gradually reduced to 70 years of age, only 50% of young people. According to the calculation, the old teacher mother's creatinine exclusion rate is 85 ml / min, is normal.
Hear this, Li teacher wrinkled eyebrows gradually stretch.
Both serum creatinine and urea nitrogen are endogenous products of nitrogen and organic matter and protein metabolism. Under normal circumstances these substances from the glomerular filtration, so doctors often use them as glomerular filtration function of the diagnosis and screening indicators. However, urea nitrogen is actually a very inaccurate indicator, affected by many factors. Such as eating more high-protein foods - meat, fish, eggs, etc., a variety of infections such as sepsis, fever, gastrointestinal bleeding can increase urea nitrogen. Li mother's blood urea nitrogen increased, is due to infection, fever, tissue decomposition caused by enhanced. With the control of infection, body temperature returned to normal, urea nitrogen will return to normal. Unfortunately, some doctors still mistakenly believe that urea nitrogen is an accurate glomerular function test. In fact, serum creatinine is a more accurate indicators of renal function, of course, according to the formula to calculate the creatinine clearance rate is better.
After listening to my explanation, Lee suddenly realized, blurted out "my mother's kidney function is normal! Right?" I nodded to answer: "Yes!"
Simple conversation, to solve the problem of teacher Li, he repeatedly thanked, satisfied to leave. I am also a kind of relaxed and happy feeling.
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