Author: Leo
Keywords: cells | kidneys | live births | term infants |
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| From google images |
Pregnant babies born before 37 weeks of gestation are called preterm infants or immature children. Most of its birth weight below 2500g, head circumference below 33cm. Its organ function and adaptability than the fuller month is poor, should give birth care special care.
According to a new study, kidney progenitor cells, also known as renal progenitor cells, from premature infants with urine may lead to the use of regenerative kidney repair in patients with nephropathy and renal injury breakthrough. The results of the study were published online March 3, 2016 in the Journal of the American Society of Nephrology, entitled "Urine of Preterm Neonates as a Novel Source of Kidney Progenitor Cells".
For humans, after about 34 weeks of pregnancy, kidney development is complete, after which the kidney cells are lost due to natural aging, disease or trauma. Scientists have been looking for ways to regenerate kidney cells, such as inducing other types of cells to show the filtration properties of these cells in the kidney.
To solve this problem, Dr. Elena Levtchenko from the University of Leuven, Belgium, and Fanny Oliveira Arcolino and his colleagues studied the presence of stem or kidney progenitor cells in the urine of healthy adults. However, they found that after kidney ripening, These undifferentiated cells are very rare. "So, we think that the urine of preterm infants may be a better alternative because their kidneys are still in development," explains Levtchenko. "We collected the urine of preterm neonates after birth Liquid, the results found in 50% of cases, urine samples containing kidney progenitor cells. "These progenitor cells can differentiate into mature kidney cells, but also has a mechanism to prevent cell death.
As a doctoral student at Dr. Levtchenko's laboratory, Arcolino said, "Preterm neonatal kidney progenitor cells may represent a powerful tool for cell therapy and regeneration of damaged kidneys." She also noted that a so-called Kidney insufficiency - the kidney can not adequately filter out the waste from the blood --- the disease is likely to be the result of premature birth. Preterm babies are given immediate access to kidney progenitor cells collected from their urine and are likely to save the lives of these newborns as a means of treatment.
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